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# Who owns OPKO HEALTH, INC. (OPK)? Elite investor 13F holders

3 tracked elite investors reported holding OPKO HEALTH, INC as of 2026-06-30, including Rubric Capital, Tudor Investment, GAMCO. Who bought, trimmed or exited each quarter, with links to the original SEC 13F filings.

3 tracked investors currently reported holding · Latest report period: 2026-06-30 · Health Care · Pharmaceuticals, Biotechnology & Life Sciences

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two…

## Reported holders and securities, including exits (up to 20)

| Investor | Security | Instrument | Report period | Filed | Value | Quantity | Units | Change | Source |
|  --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| [Rubric Capital](https://ownershiptrace.com/13f/investors/120) | OPKO HEALTH INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 71686865.00 USD | 47791243.000000 | Shares | hold | [Original filing](https://www.sec.gov/Archives/edgar/data/1687509/0001104659-26-097098-index.html) |
| [Rubric Capital](https://ownershiptrace.com/13f/investors/120) | OPKO HEALTH INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 1870491.00 USD | 1250000.000000 | Principal | hold | [Original filing](https://www.sec.gov/Archives/edgar/data/1687509/0001104659-26-097098-index.html) |
| [Tudor Investment](https://ownershiptrace.com/13f/investors/94675) | OPKO HEALTH INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 367232.00 USD | 244821.000000 | Shares | hold | [Original filing](https://www.sec.gov/Archives/edgar/data/923093/0000902664-26-003485-index.html) |
| [GAMCO](https://ownershiptrace.com/13f/investors/137) | OPKO HEALTH INC | SHARE | 2026-06-30 | 2026-08-12 00:00:00 | 262500.00 USD | 175000.000000 | Shares | hold | [Original filing](https://www.sec.gov/Archives/edgar/data/807249/0001140361-26-032508-index.html) |
| [Renaissance Technologies LLC](https://ownershiptrace.com/13f/investors/63) | OPKO HEALTH INC | SHARE | 2026-06-30 | 2026-08-13 00:00:00 | 0.00 USD | 0.000000 | Shares | exited | [Original filing](https://www.sec.gov/Archives/edgar/data/1037389/0001037389-26-000059-index.html) |

Public disclosures can be delayed, incomplete, or amended. Report period describes a position date; transaction date describes a reported transaction; filed describes submission. A recent filing or page update does not establish a current holding. A dash means unavailable or not comparable, not zero.

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