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# Who owns Xeris Biopharma Holdings, Inc. (XERS)? Elite investor 13F holders

3 tracked elite investors reported holding Xeris Biopharma Holdings, Inc as of 2026-06-30, including D.E. Shaw, Renaissance Technologies LLC, Gotham Asset Management. Who bought, trimmed or exited each quarter, with links to the original SEC 13F filings.

3 tracked investors currently reported holding · Latest report period: 2026-06-30 · Health Care · Pharmaceuticals, Biotechnology & Life Sciences

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related…

## Reported holders and securities, including exits (up to 20)

| Investor | Security | Instrument | Report period | Filed | Value | Quantity | Units | Change | Source |
|  --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| [D.E. Shaw](https://ownershiptrace.com/13f/investors/98) | XERIS BIOPHARMA HOLDINGS INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 61813683.00 USD | 7804758.000000 | Shares | add | [Original filing](https://www.sec.gov/Archives/edgar/data/1009207/0001104659-26-097217-index.html) |
| [Voss Capital](https://ownershiptrace.com/13f/investors/119) | XERIS BIOPHARMA HOLDINGS INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 0.00 USD | 0.000000 | Shares | exited | [Original filing](https://www.sec.gov/Archives/edgar/data/1730145/0001214659-26-010308-index.html) |
| [Renaissance Technologies LLC](https://ownershiptrace.com/13f/investors/63) | XERIS BIOPHARMA HOLDINGS INC | SHARE | 2026-06-30 | 2026-08-13 00:00:00 | 533308.00 USD | 67337.000000 | Shares | reduce | [Original filing](https://www.sec.gov/Archives/edgar/data/1037389/0001037389-26-000059-index.html) |
| [Gotham Asset Management](https://ownershiptrace.com/13f/investors/94672) | XERIS BIOPHARMA HOLDINGS INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 981399.00 USD | 123914.000000 | Shares | add | [Original filing](https://www.sec.gov/Archives/edgar/data/1510387/0001398344-26-014644-index.html) |
| [Tudor Investment](https://ownershiptrace.com/13f/investors/94675) | XERIS BIOPHARMA HOLDINGS INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 0.00 USD | 0.000000 | Shares | exited | [Original filing](https://www.sec.gov/Archives/edgar/data/923093/0000902664-26-003485-index.html) |

Public disclosures can be delayed, incomplete, or amended. Report period describes a position date; transaction date describes a reported transaction; filed describes submission. A recent filing or page update does not establish a current holding. A dash means unavailable or not comparable, not zero.

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