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# Who owns Praxis Precision Medicines, Inc. (PRAX)? Elite investor 13F holders

3 tracked elite investors reported holding Praxis Precision Medicines, Inc as of 2026-06-30, including Polen Capital Management, D.E. Shaw, Tudor Investment. Who bought, trimmed or exited each quarter, with links to the original SEC 13F filings.

3 tracked investors currently reported holding · Latest report period: 2026-06-30 · Health Care · Pharmaceuticals, Biotechnology & Life Sciences

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and…

## Reported holders and securities, including exits (up to 20)

| Investor | Security | Instrument | Report period | Filed | Value | Quantity | Units | Change | Source |
|  --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| [Polen Capital Management](https://ownershiptrace.com/13f/investors/61) | PRAXIS PRECISION MEDICINES I | SHARE | 2026-06-30 | 2026-08-04 00:00:00 | 2427897.00 USD | 7252.000000 | Shares | reduce | [Original filing](https://www.sec.gov/Archives/edgar/data/1034524/0001172661-26-003035-index.html) |
| [D.E. Shaw](https://ownershiptrace.com/13f/investors/98) | PRAXIS PRECISION MEDICINES I | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 1720820.00 USD | 5140.000000 | Shares | buy | [Original filing](https://www.sec.gov/Archives/edgar/data/1009207/0001104659-26-097217-index.html) |
| [Tudor Investment](https://ownershiptrace.com/13f/investors/94675) | PRAXIS PRECISION MEDICINES I | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 730847.00 USD | 2183.000000 | Shares | buy | [Original filing](https://www.sec.gov/Archives/edgar/data/923093/0000902664-26-003485-index.html) |

Public disclosures can be delayed, incomplete, or amended. Report period describes a position date; transaction date describes a reported transaction; filed describes submission. A recent filing or page update does not establish a current holding. A dash means unavailable or not comparable, not zero.

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