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# Who owns HERON THERAPEUTICS, INC. /DE/ (HPTX)? Elite investor 13F holders

3 tracked elite investors reported holding HERON THERAPEUTICS, INC. /DE/ as of 2026-06-30, including Rubric Capital, D.E. Shaw, Renaissance Technologies LLC. Who bought, trimmed or exited each quarter, with links to the original SEC 13F filings.

3 tracked investors currently reported holding · Latest report period: 2026-06-30 · Health Care · Pharmaceuticals, Biotechnology & Life Sciences

Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration. It…

## Reported holders and securities, including exits (up to 20)

| Investor | Security | Instrument | Report period | Filed | Value | Quantity | Units | Change | Source |
|  --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| [Rubric Capital](https://ownershiptrace.com/13f/investors/120) | HERON THERAPEUTICS INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 12823986.00 USD | 30046828.000000 | Shares | hold | [Original filing](https://www.sec.gov/Archives/edgar/data/1687509/0001104659-26-097098-index.html) |
| [D.E. Shaw](https://ownershiptrace.com/13f/investors/98) | HERON THERAPEUTICS INC | SHARE | 2026-06-30 | 2026-08-14 00:00:00 | 51402.00 USD | 120435.000000 | Shares | reduce | [Original filing](https://www.sec.gov/Archives/edgar/data/1009207/0001104659-26-097217-index.html) |
| [Renaissance Technologies LLC](https://ownershiptrace.com/13f/investors/63) | HERON THERAPEUTICS INC | SHARE | 2026-06-30 | 2026-08-13 00:00:00 | 643145.00 USD | 1506900.000000 | Shares | reduce | [Original filing](https://www.sec.gov/Archives/edgar/data/1037389/0001037389-26-000059-index.html) |

Public disclosures can be delayed, incomplete, or amended. Report period describes a position date; transaction date describes a reported transaction; filed describes submission. A recent filing or page update does not establish a current holding. A dash means unavailable or not comparable, not zero.

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