Who owns IONIS PHARMACEUTICALS INC (IONS)? Elite investor 13F holders

5 tracked elite investors reported holding IONIS PHARMACEUTICALS INC as of 2026-06-30, including Tweedy Browne, Renaissance Technologies LLC, D.E. Shaw, Gotham Asset Management, Ancora Advisors / Ancora Holdings. Who bought, trimmed or exited each quarter, with links to the original SEC 13F filings.

5 tracked investors currently reported holding · Latest report period: 2026-06-30 · Health Care · Pharmaceuticals, Biotechnology & Life Sciences

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; DAWNZERA for prophylaxis to prevent attacks of hereditary angioedema in adults; WAINUA for the treatment of the polyneuropathy of…

Reported holders and securities, including exits (up to 20)

Reported holders and securities, including exits (up to 20)
InvestorSecurityInstrumentReport periodFiledValueQuantityUnitsChangeSource
Tweedy BrowneIONIS PHARMACEUTICALS INCSHARE2026-06-302026-08-07 00:00:00180805859.00 USD2280311.000000SharesaddOriginal filing
Renaissance Technologies LLCIONIS PHARMACEUTICALS INCSHARE2026-06-302026-08-13 00:00:0044355936.00 USD559414.000000SharesaddOriginal filing
D.E. ShawIONIS PHARMACEUTICALS INCSHARE2026-06-302026-08-14 00:00:0023552381.00 USD297041.000000SharesreduceOriginal filing
Gotham Asset ManagementIONIS PHARMACEUTICALS INCSHARE2026-06-302026-08-14 00:00:009614071.00 USD121252.000000SharesaddOriginal filing
Tudor InvestmentIONIS PHARMACEUTICALS INCSHARE2026-06-302026-08-14 00:00:000.00 USD0.000000SharesexitedOriginal filing
Ancora Advisors / Ancora HoldingsIONIS PHARMACEUTICALS INCSHARE2026-06-302026-08-14 00:00:00175627.00 USD2215.000000SharesreduceOriginal filing

Public disclosures can be delayed, incomplete, or amended. Report period describes a position date; transaction date describes a reported transaction; filed describes submission. A recent filing or page update does not establish a current holding. A dash means unavailable or not comparable, not zero.

This public summary shows the default reporting scope. Enable JavaScript for interactive filters, charts, and additional rows.

How to read the data · Disclaimer

Read as Markdown